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Hostilities began on April 12, 1861, when Confederate forces fired upon Fort Sumter. While in the Western Theater the Union made significant permanent gains, in the Eastern Theater, the battle was inconclusive in 1861–62. The autumn 1862 Confederate campaigns into Maryland and Kentucky failed, dissuading British intervention.[citation needed] Lincoln issued the Emancipation Proclamation, which made ending slavery a war goal. To the west, by summer 1862 the Union destroyed the Confederate river navy, then much of their western armies, and seized New Orleans. The 1863 Union siege of Vicksburg split the Confederacy in two at the Mississippi River. In 1863, Robert E. Lee's Confederate incursion north ended at the Battle of Gettysburg. Western successes led to Ulysses S. Grant's command of all Union armies in 1864. Inflicting an ever-tightening naval blockade of Confederate ports, the Union marshaled the resources and manpower to attack the Confederacy from all directions, leading to the fall of Atlanta to William T. Sherman and his march to the sea. The last significant battles raged around the Siege of Petersburg. Lee's escape attempt ended with his surrender at Appomattox Court House, on April 9, 1865. While the military war was coming to an end, the political reintegration of the nation was to take another 12 years of the Reconstruction Era.
The American Civil War was one of the earliest true industrial wars. Railroads, the telegraph, steamships, and mass-produced weapons were employed extensively. The mobilization of civilian factories, mines, shipyards, banks, transportation and food supplies all foreshadowed the impact of industrialization in World War I. It remains the deadliest war in American history. From 1861 to 1865, it has been traditionally estimated that about 620,000 died but recent scholarship argues that 750,000 soldiers died, along with an undetermined number of civilians. By one estimate, the war claimed the lives of 10 percent of all Northern males 20–45 years old, and 30 percent of all Southern white males aged 18–40.
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