和訳のお願いと翻訳機非使用の要約文とハッシュタグ

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  • 急いでいるため、和訳をお願いします。翻訳機非使用で、今週中に必要です。
  • 訳の要点:- TolevamerはCDADの治療に使用されるが、商業的にはまだ利用できない。- Immunoglobulinは重症症例において使用される。- プロバイオティクスはCDADの治療に一般的に使われるが、研究はまだ十分ではない。
  • ハッシュタグ: #和訳お願い #翻訳機非使用 #今週中に必要 #CDAD治療 #プロバイオティクス
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  • ベストアンサー

和訳してほしいです。急いでいます。

単語調べても、和訳できず困っています。 今週中にやらなければいけません。 助けてください。 できれば、翻訳機を使っていない訳が知りたいです。 よろしくお願いします。 <Nonantibiotic Polymer> Not yet available commercially, tolevamer can also be considered for treating CDAD. A soluble, high-molecular-weight, anionic polymer, tolevamer works by binding C difficile toxins A and B. Suggested for use with mild to moderately severe CDAD, tolevamer is given orally 3 times daily for a total of 3 to 6 g per day. Initial trial results indicted that the polymer was fairly well tolerated, provided resolution of signs and symptoms in 67% of patients, and was associated with a lower incidence of recurrence than was vancomycin. Resolution of diarrhea was comparable to that achieved with vancomycin; however, tolevamer is also associated with an increased risk of hypokalemia. <Immunoglobulin> Immunoglobulin has been proposed as a treatment for intractable and severe cases of CDAD. In one study, patients were given 1 to 6 doses, ranging between 300 and 500 mg/kg. Of 5 patients with refractory disease, 3 had resolution of signs and symptoms within 11 days. Although this treatment looks promising, immunoglobulin is expensive and in short supply. <Probiotics> Probiotics are live organisms meant to treat particular diseases, including Helicobacter pylori infections, acute gastroenteritis, and antibiotic-associated diarrhea, including CDAD. The most commonly used probiotic agents produce lactic acid and are present in normal microflora. Examples include Saccharomyces boulardii, Lactobacillus acidophilus, and Lactobacillus plantarum. Many studies of probiotics have been done. Sullivan and Nord suggest that although S boulardii was somewhat effective, particularly in preventing recurrent CDAD, further studies are needed. Dendukuri et al similarly determined that evidence was insufficient to recommend the routine clinical use of probiotics to treat CDAD in adults.

  • 英語
  • 回答数2
  • ありがとう数2

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  • ベストアンサー
noname#175206
noname#175206
回答No.2

 専門用語間違ってても責任取りません(^^;。 「<非抗生物質ポリマー> 未だ商業利用されていないが、トレバマーはCDAD(クロストリジウム・ディフィシル関連下痢症・腸炎)にも有効と考えられている。可溶性で高分子量の陰イオンポリマーであるトレバマーはC difficile toxins A と B(適訳語なし)を結びつけることによって作用する。やや重篤なCDADに対して、トレバマーを1日に3~6グラムを3回に分けて経口摂取するという、控えめな使用が勧められる。初期試験結果では、このポリマーは非常に高い抗毒性があり、67%の患者で改善の兆候および症状があり、バンコマイシンと比べて低い再発率を示した。下痢への効能はバンコマイシンと比肩できるものであったが、トレバマーは低カリウム血症のリスクが大きかった。 <免疫グロブリン> 免疫グロブリンは、難治性で重篤なCACDの治療薬として提案されてきた。ある研究では、患者は1~6回分の服用量、300~500mg/kgを与えられている。その内5人の患者は改善せず、3人の患者は11日以内に兆候と症状に改善が見られた。この治療方法は前途に期待が持てるが、免疫グロブリンは高価で供給に難がある。 <プロバイオティクス> プロバイオティクスは生きた有機体で、ヘリコバクターピロリ菌感染、急性胃腸炎、抗生物質による下痢、CDADなどの特定の疾病の治療に用いられる。最もよく使われるプロバイオティック薬剤は、乳酸を発生するものであり、通常の微生物相に存在している。サッカロマイセス・ブラウディ(下痢症状改善機能性酵母)、好酸性乳酸桿菌、ラクトバチルス・プランタルム(植物由来の乳酸菌)などが、これに当たる。プロバイオティクスに関する多くの研究が行われてきた。SullivanとNordによれば、サッカロマイセス・ブラウディはいくらかは、特にCDAD再発予防には効果的であるものの、さらに研究が必要とのことである。Dendukuriその他らは同様に、成人のCDADに対するプロバイオティクスの長期連用を推奨するには症例が不足である、と慎重論を述べている。」 だと思いますが。

hharuca
質問者

お礼

本当にあちがとうございます>< 助かりました。

その他の回答 (1)

  • alwen25
  • ベストアンサー率21% (272/1253)
回答No.1

生化学か高分子化学か医学の論文ではないですか。 英語カテゴリでは、分かる人がいないと思います。

hharuca
質問者

お礼

すみません。 次の質問の時にはカテゴリー選択に気をつけます。

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