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ワトソンとクリックがDNA構造を発表した論文
ワトソンとクリックがDNA構造を発表した論文 (Nature, 1953)で次の文は、 いったい何をいってるのでしょうか？ We were not aware of the details of the results presented there when we devised our structure, which rests mainly though not entirely on published experimental data and stereo-chemical arguments.
- 生物学
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The previously published X-ray data on deoxyribose nucleic acid DNA に関するこれまでに発表されたX線データは are insufficient for a rigorous test of our structure. 我々の構造を厳密にテストするには不十分である。 So far as we can tell, it is roughly compatible with the experimental data, 見る限り、それ（我々の構造）は実験データと矛盾はない but it must be regarded as unproved until it has been checked against more exact results. しかし、厳密な結果と照らし合わせなければ、証明したことにはならない。 Some of these are given in the following communications. そのうちの（実験結果の）いくつかは次に続く数編の論文で扱う。 We were not aware of the details of the results presented there そこ（それらの論文の中）で提示されている結果の詳細には、我々は気づいていなかった when we devised our structure, 我々が構造を考案したときには which rests mainly though not entirely on published experimental data and stereochemical arguments. その構造は、全面的にではないが主として、出版済みの実験データと立体化学の議論に基づいている。 要するに、既出のデータに基づいて構造を組み立てたので、これから出版する論文で扱うような結果が出るとは思っていなかった、ということです。
関連するQ&A
- 生物論文の訳
下記の英文を訳してください 1)The previously published X-gen data on deoxyribose nucleic acid are insufflcient for a rigorous test of our structure.So far as we can tell,it is roughly compatible with the experimental data,but it must be regarded as unproved until it has been checked against more exact results.Some of these are given in the following communications.We were not aware of the details of the results presented there when we devised our structure,which rests mainly though not entirely on published experimental data and stereo-chemical arguments.
- ベストアンサー
- 英語
- 生物論文の訳
下記の英文を訳してください 2)It has not escaped our notice that the specific pairing we have posulated immediatbly suggests a possible copying mechanism for the genetio material.Full details of the structure,including the conditions assumed in building it,together with a set of co-ordinates for the atoms,will be published elsewhere.
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- 英語
- 和訳してください!!(後半)
The structure is an open one, and its water content is rather high. At lower water contents we would expect the bases to tilt so that the structure could become more compact. The novel feature of the structure is the manner in which the two chains are held together by the purine and pyrimidine bases. The planes of the bases are perpendicular to the fibre axis. They are joined together in pairs, a single base from one chain being hydrogen-bonded to a single base from the other chain, so that the two lie side by side with identical z-co-ordinates. One of the pair must be a purine and the other a pyrimidine for bonding to occur. The hydrogen bonds are made as follows: purine position 1 to pyrimidine position 1; purine position 6 to pyrimidine position 6. If it is assumed that the bases only occur in the structure in the most plausible tautomeric forms (that is, with the keto rather than the enol configurations) it is found that only specific pairs of bases can bond together. These pairs are: adenine (purine) with thymine (pyrimidine), and guanine (purine) with cytosine (pyrimidine). In other words, if an adenine forms one member of a pair, on either chain, then on these assumptions the other member must be thymine; similarly for guanine and cytosine. The sequence of bases on a single chain does not appear to be restricted in any way. However, if only specific pairs of bases can be formed, it follows that if the sequence of bases on one chain is given, then the sequence on the other chain is automatically determined. It has been found experimentally (3, 4) that the ratio of the amounts of adenine to thymine, and the ratio of guanine to cytosine, are always very close to unity for deoxyribose nucleic acid. It is probably impossible to build this structure with a ribose sugar in place of the deoxyribose, as the extra oxygen atom would make too close a van der Waals contact. The previously published X-ray data (5, 6) on deoxyribose nucleic acid are insufficient for a rigorous test of our structure. So far as we can tell, it is roughly compatible with the experimental data, but it must be regarded as unproved until it has been checked against more exact results. Some of these are given in the following communications. We were not aware of the details of the results presented there when we devised our structure, which rests mainly though not entirely on published experimental data and stereochemical arguments. It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material. Full details of the structure, including the conditions assumed in building it, together with a set of co-ordinates for the atoms, will be published elsewhere. We are much indebted to Dr. Jerry Donohue for constant advice and criticism, especially on interatomic distances. We have also been stimulated by a knowledge of the general nature of the unpublished experimental results and ideas of Dr. M.H.F. Wilkins, Dr. R.E. Franklin and their co-workers at King"s College, London. One of us (J.D.W.) has been aided by a fellowship from the National Foundation for Infantile Paralysis.
- 締切済み
- 英語
- 構造科学の論文
構造科学の論文を読んでいるのですが、英語も構造科学も苦手なので、論文の意味が分かりません。 一部を載せられても訳すことはできないかもしれませんが、下記の文を和訳していただけませんでしょうか？ よろしくお願いします。 We attempted to crystallize both forms, but only the trimeric NP formed crystals. The crystals showed heavy twining with a twin fraction of ,0.43 and the reflection intensity statistic ｜E2-1｜ 0.681/0.681. Initial phases were obtained in a space group of P321 using the multiple wavelength anomalous diffraction (MAD) with Samarium derivative. The true space group was P3 with three subunits in an asymmetric unit. The structure was refined to a resolution of 1.80A˚ with de-twining. The crystal structures do not contain RNA, indicating that only RNA-free NP was able to form crystals.
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- 生物学
- ある英文に関して質問です
It is no surprise, then, that we have changed the way in which we think about the eukaryotic nucleus: not long ago we could only study its structure at a rather gross level, but it is now more of an experimental laboratory. (1)最初not ～but の構文かと思ったのですが、どうも違うようです。 このnotはどういう働きなのでしょうか？訳からすると not long ago が一つだと思うのですが、働きがどうもわかりません。 (2)moreのところがわかりません。moreの後にlevelが省略だと思うのですが、なぜ訳が「むしろ」となっているのでしょか？ 以上２点よろしくお願いします。 訳「～少し前までは、やや大まかな段階でしかその構造について研究することができなかったが、それは現在ではむしろ実験室の段階にある。
- 締切済み
- 英語
- この英文について教えてください
We call a noisy signal -data that includes a lot of irregularities,often for varied and not entirely understood reasons- とあったんですがfor varied and not entirely understood reasonsの部分で分からない所があります 和訳には（完全に理解できるわけではないさまざまな理由）とあったんですが なぜこのように訳せるのでしょうか？ not entirely understood がreasonsを修飾してるとはとても思えないのですがどうしてでしょうか？ 詳しくお願いします
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- 英語
- 生物英語論文の訳
下記の英文を訳してください 1)We wish to suggest a structure for the salt of deoxyribose nucleic acid has already been proposed by Pauling and Copey.They kindly made their manuscript available to us in advance of publication.Their model consists of three inter-twind chains,with the phosphates near the fibreaxis,and the bases on the outside.In our opinion,this structure is unsatisfactory for two reasons:(1)We believe that the material which gives the X-ray diagrans is the salt,not the free acid.Without the acidic hydrogen atoms it is not clear what forces would hold the structure toegher,especially as the negatively charged phophates near the axis will repel each other.(2)Some of the van der Waals distances appear to be too small. 3)Another three-chain structure has also been suggested by Fraser(in the press).In his model the phophates are on the outside and the bases on the inside,linked together by hydrogen bonds.This atructure as described is rather ill-defined,and for this reason we shall not comment on it.
- ベストアンサー
- 英語
- 生物英語論文の訳
下記の英文を訳してください。 1)We wish to suggest a structure for the salt of deoxyribose nucleic acid has already been proposed by Pauling and Copey.They kindly made their manuscript available to us in advance of publication.Their model consists of three inter-twind chains,with the phosphates near the fibreaxis,and the bases on the outside.In our opinion,this structure is unsatisfactory for two reasons:(1)We believe that the material which gives the X-ray diagrans is the salt,not the free acid.Without the acidic hydrogen atoms it is not clear what forces would hold the structure toegher,especially as the negatively charged phophates near the axis will repel each other.(2)Some of the van der Waals distances appear to be too small. 2)Another three-chain structure has also been suggested by Fraser(in the press).In his model the phophates are on the outside and the bases on the inside,linked together by hydrogen bonds.This atructure as described is rather ill-defined,and for this reason we shall not comment on it.
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- 生物学
- 英語の文法的な構造が分かりません。
内容は理解できるのですが、文法的な構造が分かりません。 最初のThe categories and typesを受ける動詞がどれなのか教えていただけると助かります。 The categories and types that we isolate from the world of phenomena we do not find there because they stare every observer in the face; on the contrary, the world is presented in a kaleidoscopic flux of impressions which has to be organized by our mindsーand this means largely by the linguistic systems in our minds.
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- 英語
- 生物論文の和訳
下記の論文を訳してください。 1)We wish to put forward a radically different structure for the salt of deoxyribose nucleic acid.This structure has two helical chains cach colied round the same axis(see diagram).We have made the usual chemical assumptions,namely,that each chain consists of phophates di-ester groups joining B-D-deoxy-ribofuranose residues with 3',5' linkages.The two chains (but not their bases) are related by a dyad perpendicular to the fibreaxis.Both chains follow right-handed helices,but owing to the dyad the sequences of the atoms in the two chains run in opposite directions.Each chains loosely resembles Fur-berg's model No.1 ; that is,the bases are on the inside of the helix and the phophates on the outside.The configuration of the sugar and the atoms near it is close to Furberg's 'standard configuration',the sugar being roughly perpendicular to the attached base.
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- 生物学
お礼
ありがとうございます We were not aware of the details of the results presented there when we devised our structure, のところが、なぜわざわざ「我々が考案したときには気が付いていなかった」などといっているのか、 腑に落ちないんですけどねえ 何をいいたいのか