New Research Finds Link Between Exercise Frequency and Stroke Risk| OKWAVE

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The researchers also looked at the data according to gender. After the researchers accounted for age, race, socioeconomic factors (education and income) and stroke risk factors, the results revealed that men who exercised at least four times a week still had a lower risk of stroke than men who exercised one to three times per week. In contrast, there was no association between frequency of exercise and stroke risk among women in the study. However, there was a trend towards a similar reduction in stroke risk for those who exercised one to three times a week and four or more times a week compared to those who were inactive. “This could be related to differences in the type, duration, and intensity of physical activity between men and women,” said Dr. Howard. “This could also be due to differences in the perception of what is intense physical activity enough to work up a sweat.” The results should encourage doctors to stress the importance of exercise when speaking with their patients, Dr. Howard said. “Physical inactivity is a major modifiable risk factor for stroke. This should be emphasized in routine physician check-ups along with general education about the benefits of exercise on stroke risk factors including high blood pressure, diabetes and being overweight or obese,” she said. The study suggests that men should consider exercising at least four times a week. REGARDS will continue to assess stroke risk factors to look for long-term patterns in the study population. “Findings from this study, including the current physical activity results, will ultimately help us to identify potential targets for immediate intervention as well as for future clinical trials aimed at preventing stroke and its consequences,” said Dr. Moy.

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“Unlike previous investigations, we were able to assess association of consumption of caffeinated and non-caffeinated beverages, and we identify caffeine as the most likely candidate of any putative protective effect of coffee,” said lead researcher Michel Lucas, research fellow in the Department of Nutrition at HSPH. The authors reviewed data from three large U.S. studies and found that the risk of suicide for adults who drank two to four cups of caffeinated coffee per day was about half that of those who drank decaffeinated coffee or very little or no coffee. Caffeine not only stimulates the central nervous system but may act as a mild antidepressant by boosting production of certain neurotransmitters in the brain, including serotonin, dopamine, and noradrenaline. This could explain the lower risk of depression among coffee drinkers that had been found in past epidemiological studies, the researchers reported. In the new study, researchers examined data on 43,599 men enrolled in the Health Professionals Follow-Up Study (HPFS) (1988–2008), 73,820 women in the Nurses’ Health Study (NHS) (1992–2008), and 91,005 women in the Nurses’ Health Study II (NHSII) (1993–2007). Caffeine, coffee, and decaffeinated coffee intake was assessed every four years by questionnaires. Caffeine consumption was calculated from coffee and other sources, including tea, caffeinated soft drinks, and chocolate. However, coffee was the major caffeine source — 80 percent for NHS, 71 percent for NHS II, and 79 percent for HPFS. Among the participants in the three studies, there were 277 deaths from suicide. In spite of the findings, the authors do not recommend that depressed adults increase caffeine consumption, because most individuals adjust their caffeine intake to an optimal level for them and an increase could result in unpleasant side effects. “Overall, our results suggest that there is little further benefit for consumption above two to three cups/day or 400 mg of caffeine/day,” the authors wrote. The researchers did not observe any major difference in risk between those who drank two to three cups of coffee per day and those who had four or more cups a day, most likely due to the small number of suicide cases in these categories. However, in a previous HSPH coffee-depression study published in JAMA Internal Medicine, the investigators observed a maximal effect among those who drank four or more cups per day. One large Finnish study showed a higher risk of suicide among people drinking eight or nine cups per day. Few participants in the two HSPH studies drank such large amounts of coffee, so the studies did not address the impact of six or more cups of coffee per day.

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There was one large difference between the animal study and the human research projects mentioned in the article: the researchers controlled what the animals in the earlier studies ate, while the humans reported their eating behavior. Thus, as Dr. Bartke mentions, there is a question about the quality of the data. As long as the researchers kept careful records on what was fed to the animal subjects and prevented the animals from getting food from other sources, they could be confident of the food intake measurement. Humans, however, are not lab rats. It is not ethical, or generally possible, to completely control the environment that a human experiences. In this case, it was likely not economically feasible to control the diet for the subjects in the “diet group.” As a result, the researchers relied on self-reported data from these subjects. It is very unlikely that all of the members who reported that they cut their caloric intake by 30% actually did so. If the control their diet and observe their action, then we might be able to accept that the members of the group actually reduced their calories by 30%. However, one would then worry that a group of people who could take three months to go to a lab environment might not be representative of the general population.

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Field work, or the collection of data, can be a very exciting part of a researcher’s career. At the same time, field work can be very tedious because doing it properly requires a lot of patience. A sociologist may go to a workplace and spend all day observing how the people there act, or may interview hundreds of people as part of a survey. In marine biology, field work may consist of going out on the ocean to capture, tag, and release animals. An archaeologist might supervise a dig, where ancient objects are unearthed, classified, and archived. As the above suggests, field work takes a lot of planning and organization. Also, it is important to follow routine procedures to make sure that the data are collected properly. Sometimes, however, a great discovery is made, and the atmosphere at the site becomes electric. For example, it must have been incredibly exciting for Gen Suwa to find the first specimen of A. ramidus, but then two years of painstaking work was needed to find enough fossils to construct the skeleton. Both sides of field work are necessary. The exciting discoveries show the researchers that they are on the right track, and the routine procedures support the validity of the newly-made discoveries.

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Interestingly, studies based on the uranium series as well as other decay series put the age of the oldest rocks and, therefore, probably the age of Earth itself at A, or B years. この英文を和訳してほしいです。

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In this study, the researchers used "a powerful mathematical algorithm" to find the SNPs that would be most useful for them. It is increasingly common for biologists and other scientists to use algorithms, or step-by-step procedures, in analyzing date. An algorithm is often shown as a flowchart with decision points. At each decision point, the process will go in one direction or another. For example, after you read an email message you may make a simple decision: "Should I reply to this message?" If the answer is "Yes, reply" then the next decision point is "Should I reply immediately?" On the other hand, if the answer is "No, do not reply" then the next decision point is "Should I archive this message or throw it away?" That is, each alternative leads to its own path. At the end of the process, you will have either 1) read, replied to, and archived the message, 2) read, replied to, and deleted the message, 3) read and archived the message, or 4) read and deleted the message. Obviously, if such a simple decision can be charted out with so many alternatives and consequent final decisions, the complicated environment in which scientists work will require highly sophisticated algorithms. Without the use of computer-driven algorithms, there would not be enough time to explore all of the potential decision paths. Thus, new disciplines such as computational biology have arisen in order to support researchers in their quest for knowledge.

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英文の和訳をお願いします。 A useful tool at this point would be an account of bulimia that is both plausible and parsimonious. It should be plausible in that it fits the known facts about bulimia, and it should be parsimonious in that the phenomenon is not overexplained by many concomitant, nonindependent forces. An appropriate theory should define the people at risk for the disorder as well as those not at risk. A good theory should also describe the process of acquiring the symptoms themselves. None of the existing theories can do all of these things. Although the sociocultural approach can define who is at risk, it neither effectively defines who is not at risk nor how bulimics acquire the binge-eating behavior. The clinical perspective is well suited to defining who is at risk and who is not at risk but has not carefully spelled out how it is that the symptoms are acquired. The epidemiological approach, like the clinical approach, is better suited to defining risk factors than to describing processes of symptom acquisition. I wish to propose a model that is well suited to describing the symptom acquisition process, based on social psychological processes.

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Weight concentrated around the abdomen and in the upper part of the body (the apple shape) poses a higher health risk than fat that settles around the hips and flank (the pear shape). Fat cells in the upper part of the body appear to have different qualities from those found in the lower parts. In fact, studies suggest a higher risk for diabetes in people with the "apple shape" and lower risk in those who are "pear shaped."

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次の英文を和訳していただけませんでしょうか。宜しくお願い致します。 To show a total manufacturing concept, that describes the control mechanisms for critical and non-critical dimensions/parameters as prescribed by M Corporation requirements, historical problems and/or failure analysis studies.

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The article mentions that it took 17 years from the beginning of the investigation to the publication of the 11 papers on Ardi in 2009. During that time only one paper was published by the team members, in 1994. It is interesting that the team did not publish papers on the research for 15 years, for we live in the era of “publish or perish” – in other words, professors understand that they need to publish academic articles in order to keep their jobs, or at least to be able to advance their careers. True, 47 of the 70 investigators on the team were listed as authors on the 11 papers. Also, the publication of the papers all at once essentially guaranteed that the papers were given a lot of attention. Still, it is encouraging that the universities and other institutions that funded the research continued to support the team members despite the lack of papers. After all, “publish or perish” is largely due to the need for universities to be recognized as places where a lot of research is being done. High levels of publication lead to high evaluations, which helps attract students and funding to a particular university. The presence of good students and large research budgets help the school maintain its excellence. So the term “publish or perish” may not be quite as cynical as it first sounds.

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When the tricky diagnosis of appendicitis is considered, blood tests and a urinalysis are required. The patient's blood is put into different colored tubes, each with its own additive depending on the test being performed: •A purple-top tube is used for a complete blood count (CBC). A CBC measures: 1) The adequacy of your red blood cells, to see if you are anemic. 2) The number and type of white blood cells (WBCs), to determine the presence of infection. 3) A platelet count (platelets are a blood component necessary for clotting) •A red-top tube is used to test the serum (the liquid or non-cellular half of your blood). •A blue-top tube is used to test your blood's clotting. The tests in your case indicate that you have an elevated WBC count. This is a sign of a bacterial infection, and bacterial infections are commonly associated with appendicitis. At this point, the emergency physician may request that you not eat or drink anything. The reason is that appendicitis is treated by surgery, and an empty stomach is desirable to prevent some complications of anesthesia. When the emergency physician has all the information he can obtain, he makes a determination of the most likely diagnosis from his differential diagnosis. Alternately, he may decide that he does not have enough information to make a decision and may require more tests. At this point, he speaks to a general surgeon -- the appropriate consultant in this case. The surgeon comes to see you and performs a thorough history, physical exam, and review of your lab data. She examines your symptoms: pain and tenderness in the right, lower abdomen, vomiting, low-grade fever and elevated WBC count. These symptoms all point to appendicitis. The treatment of appendicitis is removal of the appendix, or an appendectomy. The surgeon explains the procedure, including the risks and benefits. You then sign a consent form to document this and permit her to operate on you. The vast array of people caring for patients in an emergency department can be quite confusing to the average health care consumer -- as confusing as if you were watching your first baseball game ever and no one was around to explain all those players. Additionally, most people are uncertain of the training and background necessary to become a member of the emergency-department team. Well, here's the scorecard. The emergency physician comes to the team after spending four years in college studying hard to get as high a GPA (grade point average) as possible in order to get accepted into medical school. Medical school is a four-year course of study covering all the essentials of becoming a physician. It generally includes two years of classroom time, followed by two years rotating through all the different specialties of medicine. Toward the end of medical school, each medical student must select a particular specialty (emergency medicine, family practice, internal medicine, surgery, pediatrics, etc.). The medical student then completes an internship (one year) and residency (two to three additional years) in order to be a specialist in emergency medicine. Physicians must pass an all-day written exam and an all-day oral exam to become board certified in emergency medicine. As of 2001, there were approximately 32,000 emergency physicians practicing in the United States, of which 17,000 were certified by the American Board of Emergency Medicine.

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An experimental therapy that fed children with peanut allergies small amounts of peanut flour has helped more than 80 per cent of them safely eat a handful of the previously worrisome nuts. Although experts say the results of the carefully monitored study are encouraging, they warn it isn't something that parents should try at home. Peanut allergies are on the rise globally and affect about 1 in 50 children, mostly in high-income countries. The consequences can be life-threatening -- peanuts are the most common cause of fatal food allergy reactions. There is no way to avoid a reaction other than just avoiding peanuts. Allergy shots used for environmental triggers like pollen are too risky. Doctors at Addenbrooke's Hospital in Cambridge started by giving 99 children aged seven to 16 with severe peanut allergies a tiny 2-milligram dose of a special peanut flour mixed into their food. Slowly they increased that amount to 800 milligrams. The dose increases were given at a research facility where the children were observed for any dangerous side effects -- the most frequent were itchiness in the mouth, stomach pains or nausea. After six months of treatment, more than 80 per cent of the children can now safely eat five peanuts at a time. "This made a dramatic difference to their lives," said Dr. Andrew Clark of the University of Cambridge in Britain, who led the research. "Before the study, they could not even tolerate tiny bits of peanuts and their parents had to read food labels continuously." The intention of the treatment isn't to help kids eat large amounts of peanuts, but to prevent a life-threatening allergic reaction in case they accidentally eat trace amounts. Clark said the treatment works by retraining the patients' immune systems so they can gradually build up a tolerance to peanuts, though he guessed they might need to keep taking it for several years. He and colleagues plan to offer the treatment soon in a special peanut allergy clinic as well as beginning larger studies.

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英文の和訳です。 The difficulty of the training tasks increased as the participants improved to continuously challenge their cognitive performance and maximize any benefits of training. が上手く訳せません。この場合の「as」の意味がよくわからないんです。和訳お願いします。

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The American Journal of Public Health continues to be a leader in the field of Public Health, publishing quality research that is highly cited. Our 2013 impact factor is 4.229, an increase over last year, and ranks the journal #4 out of 136 titles in the Public, Environmental and Occupational Health category in the Social Sciences Citation Index and #14 of 160 titles in the same category for the Science Index. Dr. John Ruffin, Director of the National Institute on Minority Health and Health Disparities, was interveiwed by Dr. Stephen Thomas and Dr. Sandra Quinn of the University of Maryland Center for Health Equity and Guest Editors of this theme issue. Dr. Ruffin discusses a variety of issues related to the importance of including minorities in research, the changing demographics of the US population, new challenges for researchers, the value of community participation, and how minority inclusion research is "not one size fits all." In the wake of the tragic shooting at the Washington, DC, Naval Yard on Monday, September 16, 2013, the journal has compiled a collection of papers and other resources to help promote awareness and policy change surrounding gun violence, veterans health, and suicide. For those seeking more information on organizations that work with victims of gun violence and other types of violence, please consult Chapter 11 from APHA's book, Confronting Violence. Additionally, the following articles and content have been unlocked to public viewing: Shim et al: Primary Care, Behavioral Health, and Public Health: Partners in Reducing Mental Health Stigma. Lewiecki et al: Suicide, Guns, and Public Policy. Siegel et al: The Relationship Between Gun Ownership and Firearm Homicide Rates in the United States, 1981–2010. Henderson et al: Mental Illness Stigma, Help Seeking, and Public Health Programs. Magruder et al: The Role of Pain, Functioning, and Mental Health Suicidality Among Veterans Affairs Primary Care Patients. Keyes et al: To Flourish or Not: Positive Mental Health and All-Cause Mortality. Kaplan et al: Suicide Risk and Precipitating Circumstances Among Young, Middle-Aged, and Older Male Veterans. Vernick et al: Availability of Litigation as a Public Health Tool for Firearm Injury Prevention: Comparison of Guns, Vaccines, and Motor Vehicles. Branas et al: Investigating the Link Between Gun Possession and Gun Assault. Fledderus et al: Mental Health Promotion as a New Goal in Public Mental Health Care: A Randomized Controlled Trial of an Intervention Enhancing Psychological Flexibility. Druss et al: Mental Health Promotion in a Reformed Health Care System. Davis et al: Reduced Mortality Among Department of Veterans Affairs Patients With Schizophrenia or Bipolar Disorder Lost to Follow-Up and Engaged in Active Outreach to Return for Care. Lane et al: Prevalence of Perceived Stress and Mental Health Indicators Among Reserve-Component and Active-Duty Military Personnel. Ilgen et al: Patterns of Treatment Utilization Before Suicide Among Male Veterans With Substance Use Disorders. Katz et al: Lessons Learned From Mental Health Enhancement and Suicide Prevention Activities in the Veterans Health Administration.

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英文の和訳をお願いします。 The sudden and dramatic appearance of bulimia as a set of clinical symptoms has prompted a great deal of psychological and psychiatric theorizing about the roots of the syndrome. Surprisingly little is known about the causes of bulimia. Bulimics seem to be virtually indistinguishable from nonbulimic controls on a surprising number of variables, such as height, weight, sex role orientation, and even ego involvement with food and eating. There have been three general classes of explanations put forward: a sociohistorical/cultural approach, a clinical/psychiatric approach, and an epidemiological/risk factors approach.

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Both the print and the online-only articles have been combined into one E-Reader friendly product, enabling access to the complete Journal issue. 10/09/2013: The December 2012 e-Reader issues are now available for download. We have two different versions available: one for the Kindle and one for all devices. APHA Members access the e-Reader product as a benefit and must follow a dual sign-on process. Watch the video tutorial here or here. All other must purchase access and must have a registered account with our website. FREE: The full version of the July 2012 Journal issue is available for free for your E-Reader and E-Reader enabled mobile device. Features include: Both the print and online-only articles, full advertisements, easy navigation from article to article, easy navigation within articles, a streamlined reading experience that puts fully linked tables, figures, and references at the end of the issue, as well as standard E-Reader features such as top-menu navigation, bookmarking and note-taking capabilities, and "double tap" access to all images and figures. Additionally, URLs and email links are fully functional on devices with Internet accessibility. The American Journal of Public Health® (AJPH®) is dedicated to the publication of original work in research, research methods, and program evaluation in the field of public health. The mission of the journal is to advance public health research, policy, practice, and education. Celebrating over 100 years, AJPH is the official journal of the American Public Health Association. Additionally, AJPH was voted one of the 100 Most Influential Journals in Biology & Medicine over the last 100 Years by the Special Libraries Association. Visit us on our Facebook or Twitter page for updates on current research, a look back at earlier research, articles in the news, and more! The Facebook and Twitter pages, updated daily, offer another great way to keep up to date with the Journal and the American Public Health Association. AJPHTalks continues its extended coverage of AJPH material, highlighting important research and public health topics, providing notices of Journal updates, and noting key policy changes within the Journal. AJPHTalks is a free access blog and will be available to all. It features RSS subscription feeds and social media links via Google Plus, Facebook, and Twitter. Subscribe today and stay tuned for new updates!

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　　　　We evaluated <P(e, 0)> for 12 cases of e between 0 and 6: e=0.0, 0.01, 0.1, 0.5, 0.75, 0.9, 1.0, 1.2, 1.5, 2.0, 4.0, and 6.0. As for r_p, we considered three cases: r_p=0.005, 0.001, and 0.0002. These are representative values of radii of protoplanets at the Earth, Jupiter, and Neptune orbits regions, respectively. The numbers of collision orbits found by our orbital calculation are shown in Table 3 for representative values of e. From Table 3 we can expect the statistical errors in the evaluated collisional rate to be within 5% for the cases of e≦1.5 and within 8% for e=4 and 6; they are smaller than that of the previous studies by Nishida (1983) and by Wetherill and Cox (1985). 　　　The calculated collisional rate is summarized in terms of the enhancement factor defined by Eq. (27) and shown in Fig.11, as a function of e and r_p. From Fig.11 one can see that the collisional rate is always enhanced by the effect of solar gravity, compared with that of the two-body approximation <P(e,0)>_2B. In particular, in regions where e≦1, R(e,0) is almost independent of e, having a value as large as 3. At e≦1, R(e,0) has a notable peak beyond which the enhancement factor decreases gradually with increasing e. For large values of e, i.e., e≧4, <P(e,0)> tends rapidly to <P(e,0)>_2B. As seen in the next section, we will find a similar dependence on e even in the three-dimensional case (i≠0) as long as we are concerned with cases where i≦2. お手数ですが、よろしくお願いします。

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Dr. Frank Guenther is a cognitive neuroscientist who studies speech production, speech perception, and sensory-motor control. He and his team helped a completely paralyzed but conscious patient communicate with the use of brain sensors. First, the researchers watched the patient’s brain activity by using functional MRI (fMRI) as he tried to say certain vowels. Next, they implanted an electrode into the part of the man’s brain that deals with speech production. The electrode can sense brain activity very quickly and transmit it instantaneously to a machine that can show which vowels the patient is thinking about. After more vowels and consonants are added to the list of understood letters, it is hoped that the patient will be able to communicate whole words to the researchers. Other projects have used electrodes to allow a paralyzed person to move a robotic arm, but this is the first project to have a specifically designed brain-computer interface for speech. A future patient may have additional electrodes implanted so that more information can be transmitted from the speech-production area of the brain to the researchers, leading to deeper communication. よろしくお願いします＾＾；

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In 2005,Kentucky Fried Chicken(KFC)-of all places-conducted a comprehensive study of personality . Using KFC customers as subjects and different barbecue sauces as test factors, KFC’s research revealed a direct link between flavor preference and personality. For example, people who prefer the sweet and tangy Honey BBQ sauce are “winners who do not accept defeat and have little tolerance for other’s foolishness”. Customers who choose the hotter Sweet and Spicy sauce, on the other hand, are outgoing, flamboyant people who enjoy taking risking put exciting new experiences at work, at play, and in romance. Although we perhaps shouldn’t take KFC’s findings too seriously-it is, after all, a commercial come-on-the results coincide with a well-known fact in psychological circles: that our personal preferences tell us a lot about who we really are. This is backed up by a recent study led by Professor Adrian North of Scotland. Researchers asked 36,000 men and women of all ages from all over the world to rate different musical styles. Then the subjects took detailed personality tests. Jazz fans proved to be creative, sociable, and verbally gifted, classical music buffs were thoughtful and quiet, and country music lovers were diligent, friendly, and dependable. The big surprise was heavy metal fans. While the conventional stereotype sees them as dangerous to themselves and society, North’s study found them to be gentle and “quite delicate.” As Psychology Today puts it: “We consume books, music, and visual art primarily to fulfill the internal emotional needs that are visual fundamental to our personalities. But we also make such choices based on a desire to crave out identities. But we also make such choices based on a desire to carve out identities for ourselves-to articulate the stories of our lives. By the same token we look for those stories in others….and intuitively feel that we can judge others by their tastes. Unfortunately, those judgments are often wrong”

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Just last year, Toyota announced four robots made to help paralyzed patients walk or balance themselves. The company plans to commercialize the robots sometime in 2013. Pictured above is one of the four robots, the Balance Training Assist. The robot acts as a two-wheeled balancing game. The machine displays one of three sports games on a monitor and requires the patient to make moves in the game by shifting his/her weight on the robot. Other medical robots developed by Toyota include The Walk Training Assist robot and the Independent Walk Assist robot. The Walk Training Assist robot mounts on a paralyzed leg and detects movement of the hips through sensors at the thigh and foot. The robot helps the knee swing and the leg move forward to facilitate walking. The Independent Walk Assist robot is designed for walking training. In addition to helping the leg bend and move forward, the robot supports the patient's weight. The robot adjusts to support less weight as the patient's walking improves. The Assist robots can also monitor metrics, such as joint angles, allowing physicians to more easily track a patient's progress.

New Research Finds Link Between Exercise Frequency and Stroke Risk

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New Research Finds Link Between Exercise Frequency and Stroke Risk

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